Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | F2R | P25116 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977128 | 0.91 | F2R (0.45) | MRGPRX1MAPTF2RALDH1A1LMNA | |
| SCHEMBL19976912 | 0.88 | MRGPRX1 (0.48) | MRGPRX1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19976937 | 0.87 | TP53 (0.52) | MRGPRX1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19976991 | 0.87 | MRGPRX1 (0.47) | MRGPRX1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19976896 | 0.84 | SMN1; SMN2 (0.47) | MRGPRX1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19977126 | 0.81 | MRGPRX1 (0.44) | MRGPRX1ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL16993907 | 0.80 | MRGPRX1 (0.42) | MRGPRX1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19977043 | 0.78 | MAPT (0.53) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL19976988 | 0.78 | MEN1 (0.52) | MRGPRX1MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL19977073 | 0.78 | PGR (0.52) | MAPTF2RALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |