Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976937 | 0.91 | TP53 (0.52) | MAPTHTTTP53MEN1KMT2A | |
| SCHEMBL19977128 | 0.87 | F2R (0.45) | MAPTHTTMEN1KMT2ANPC1 | |
| SCHEMBL19977005 | 0.84 | ALDH1A1 (0.44) | MAPTTP53MEN1KMT2ANPC1 | |
| SCHEMBL16994012 | 0.83 | CTSL (0.46) | MAPTHTTLMNAPOLBHPGD | |
| SCHEMBL24862919 | 0.82 | HTT (0.44) | MAPTHTTTP53MEN1KMT2A | |
| SCHEMBL19976973 | 0.82 | KMT2A (0.44) | MAPTHTTTP53MEN1KMT2A | |
| SCHEMBL19976912 | 0.79 | MRGPRX1 (0.48) | MAPTHTTTP53MEN1KMT2A | |
| SCHEMBL19977042 | 0.78 | KMT2A (0.52) | MAPTTP53MEN1KMT2ANPC1 | |
| SCHEMBL19977052 | 0.78 | MRGPRX1 (0.47) | MAPTHTTTP53MEN1KMT2A | |
| SCHEMBL19976991 | 0.78 | MRGPRX1 (0.47) | MAPTHTTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |