Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157596 | 0.81 | MAPT (0.64) | NOTUMPOLBTSHRALDH1A1MAPT | |
| SCHEMBL160329 | 0.81 | ALDH1A1 (0.58) | NOTUMPOLBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL10202736 | 0.78 | TSHR (0.63) | NOTUMPOLBTSHRALDH1A1MAPT | |
| SCHEMBL11307310 | 0.76 | NOTUM (0.68) | NOTUMPOLBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL2165230 | 0.73 | ALDH1A1 (0.56) | NOTUMPOLBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL30204966 | 0.73 | MAPT (0.61) | NOTUMPOLBTSHRALDH1A1MAPT | |
| SCHEMBL173546 | 0.73 | GAA (0.60) | NOTUMSIGMAR1ALDH1A1MAPTKMT2A | |
| SCHEMBL28545525 | 0.72 | NOTUM (0.57) | NOTUMPOLBSIGMAR1TSHRALDH1A1 | |
| SCHEMBL5006023 | 0.72 | TSHR (0.75) | NOTUMPOLBTSHRALDH1A1MAPT | |
| SCHEMBL13473681 | 0.72 | NOTUM (0.57) | NOTUMPOLBSIGMAR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |