SCHEMBL173546

SCHEMBL173546

CCNC(=S)N1CCCc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.60
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
MAPT P10636 6/20 0.58
ALDH1A1 P00352 6/20 0.58
LMNA P02545 1/20 0.58
MGLL Q99685 1/20 0.57
MAPK1 P28482 1/20 0.56
NOTUM Q6P988 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.54
SIGMAR1 Q99720 1/20 0.54
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160329 0.91 ALDH1A1 (0.58) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL2165230 0.79 ALDH1A1 (0.56) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL4869697 0.79 TP53 (0.58) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL4871870 0.79 MAPT (0.57) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL29941498 0.77 MGLL (0.62) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL2165282 0.76 ALDH1A1 (0.52) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL4869536 0.76 KMT2A (0.59) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL4871145 0.76 KMT2A (0.48) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL4867619 0.76 MEN1 (0.64) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL5356749 0.76 MAPT (0.73) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-20150327552-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2015-11-19 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
WO-2012030986-A2 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY (US) 2012-03-08 WO disclosed
WO-2012030986-A2 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY (US) 2012-03-08 WO disclosed
WO-2012006276-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-12 WO disclosed
WO-2012006276-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT GAA 104/4885MEN1 4199/4885KMT2A 522/4885
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT GAA 104/4885MEN1 4199/4885KMT2A 522/4885
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES PGLS, BLVRB, AADAC GAA 778/4885MEN1 4574/4885KMT2A 702/4885
US-20150327552-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT GAA 104/4885MEN1 4199/4885KMT2A 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.