Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977061 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL19977012 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL24863070 | 0.85 | KMT2A (0.42) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL19977108 | 0.83 | POLB (0.42) | ALDH1A1KMT2AHPGDMEN1NPSR1 | |
| SCHEMBL19977056 | 0.83 | KDM4E (0.59) | ALDH1A1KMT2AHPGDKDM4EGAA | |
| SCHEMBL23594204 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL19977132 | 0.81 | ENPP1 (0.45) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL19977027 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KMT2AHPGDKDM4EGAA | |
| SCHEMBL19977131 | 0.80 | MAP4K1 (0.51) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL19977130 | 0.78 | L3MBTL1 (0.44) | ALDH1A1KMT2AKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |