SCHEMBL19977174

SCHEMBL19977174

Cc1ccc2c(c1)C1(c3cc(C)ccc3-c3ccc(Cl)cc31)c1cc(Cl)ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.46
AKR1A1 P14550 2/20 0.41
AKR1B1 P15121 2/20 0.41
S100A4 P26447 2/20 0.40
CES1 P23141 2/20 0.37
PPOX P50336 1/20 0.36
HSD11B1 P28845 1/20 0.36
TP53 P04637 1/20 0.36
PGR P06401 1/20 0.36
CYP3A4 P08684 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
ALKBH3 Q96Q83 1/20 0.34
AGTR1 P30556 1/20 0.33
TGM2 P21980 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20121806 0.91 PDK2 (0.49) PDK2AKR1A1AKR1B1S100A4
SCHEMBL21038431 0.88 PDK2 (0.43) PDK2AKR1A1AKR1B1S100A4PGR
SCHEMBL19286810 0.87 PDK2 (0.47) PDK2TP53CYP3A4CA1CA2
SCHEMBL25815179 0.86 PDK2 (0.41) PDK2AKR1A1AKR1B1S100A4HSD11B1
SCHEMBL27043605 0.83 SMN1; SMN2 (0.46) PDK2AKR1A1AKR1B1S100A4CYP3A4
SCHEMBL22797700 0.83 PDK2 (0.42) PDK2AKR1A1AKR1B1S100A4PGR
SCHEMBL16435207 0.82 PDK2 (0.42) PDK2AKR1A1AKR1B1S100A4CES1
SCHEMBL20687343 0.82 PDK2 (0.38) PDK2AKR1A1AKR1B1
SCHEMBL20687321 0.81 PDK2 (0.38) PDK2AKR1A1AKR1B1
SCHEMBL22797329 0.78 PARP1 (0.41) PDK2AKR1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363260-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-9923147-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-20 US disclosed