Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.38 |
| ▸ | RORA | P35398 | 4/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | RORB | Q92753 | 4/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978109 | 0.89 | DNMT1 (0.39) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL19978114 | 0.85 | PGR (0.34) | PGRRORARORCRORB | |
| SCHEMBL19978100 | 0.85 | GSK3B (0.39) | DNMT1 | |
| SCHEMBL19978105 | 0.84 | PRKD3 (0.31) | — | |
| SCHEMBL19978115 | 0.83 | GRIK2 (0.39) | PGR | |
| SCHEMBL19978120 | 0.81 | PGR (0.37) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL19978107 | 0.74 | PGR (0.33) | PGRRORARORCRORB | |
| SCHEMBL19978097 | 0.74 | GSK3B (0.39) | DNMT1 | |
| SCHEMBL23463263 | 0.73 | DNMT1 (0.33) | PGRRORARORCRORBDNMT1 | |
| SCHEMBL24431073 | 0.72 | PGR (0.38) | PGRRORARORCRORBDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079841-A1 | METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079841-A1 | METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | PCBP1, SOD1, PCLAF | PGR 1170/4885RORA 4063/4885RORC 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.