Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978240 | 0.74 | KDM4E (0.55) | MAPTKDM4ELMNAMEN1KMT2A | |
| Iodide SCHEMBL29763642 | 0.73 | MEN1 (0.54) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL28795459 | 0.69 | KMT2A (0.49) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL1655723 | 0.68 | KMT2A (0.34) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL217044 | 0.67 | MAPT (1.00) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL29638873 | 0.66 | MEN1 (0.37) | MEN1KMT2AHTTCYP3A4CYP1A2 | |
| SCHEMBL17689028 | 0.66 | KDM4E (0.35) | MAPTKDM4EHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28420480 | 0.65 | MAPT (0.94) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL129944 | 0.65 | MAPT (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL3341425 | 0.65 | MAPT (0.71) | MAPTKDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2021-02-11 | — | — | US | disclosed |
| US-10633542-B2 | Azacyanine dyes and use thereof | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2020-04-28 | — | — | US | disclosed |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INTRACE MEDICAL SA (CH) | 2019-09-26 | — | — | US | disclosed |
| WO-2019180475-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-09-26 | — | — | WO | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | MAPT 3491/4885KDM4E 783/4885LMNA 3815/4885 |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | MAPT 3491/4885KDM4E 783/4885LMNA 3815/4885 |
| US-10633542-B2 | Azacyanine dyes and use thereof | INMT, AZI2, MYADM | MAPT 3491/4885KDM4E 783/4885LMNA 3815/4885 |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | MAPT 3491/4885KDM4E 783/4885LMNA 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.