Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22970332 | 0.76 | CYP1A2 (0.35) | KMT2APDK2CYP1A2CYP2C19 | |
| SCHEMBL21401727 | 0.71 | MEN1 (0.32) | KMT2AMEN1 | |
| Quinoline SCHEMBL27529701 | 0.70 | ALDH1A1 (0.52) | KMT2ANPC1L3MBTL1MEN1KDM4E | |
| SCHEMBL19978242 | 0.69 | MEN1 (0.41) | KMT2ANPC1L3MBTL1MEN1KDM4E | |
| SCHEMBL4619322 | 0.68 | PSMB5 (0.40) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL19978240 | 0.68 | KDM4E (0.55) | KMT2ANPC1L3MBTL1MEN1KDM4E | |
| SCHEMBL19978239 | 0.68 | MAPT (0.47) | KMT2ANPC1L3MBTL1MEN1KDM4E | |
| SCHEMBL101153 | 0.68 | CASP3 (0.47) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| SCHEMBL1335900 | 0.67 | PDK2 (0.43) | KMT2ANPC1L3MBTL1MEN1KDM4E | |
| Iodide SCHEMBL14844987 | 0.67 | CASP3 (0.46) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284090-A | Electron acceptor and fluoboric cyanine fluorescent dye as well as preparation method and application thereof | 四川大学华西医院 | 2023-06-23 | — | — | CN | disclosed |
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2021-02-11 | — | — | US | disclosed |
| US-10633542-B2 | Azacyanine dyes and use thereof | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2020-04-28 | — | — | US | disclosed |
| WO-2019180475-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-09-26 | — | — | WO | disclosed |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INTRACE MEDICAL SA (CH) | 2019-09-26 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20060099638-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2006-05-11 | — | — | US | disclosed |
| US-20060004188-A1 | Intermediates and the synthesis of modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2006-01-05 | — | — | US | disclosed |
| US-6977305-B2 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-6974873-B2 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20050112770-A1 | Method for optical measurement of multi-stranded nucleic acid | FUJI PHOTO FILM CO., LTD. | 2005-05-26 | — | — | US | disclosed |
| EP-1362894-A2 | Method for optical measurement of multi-stranded nucleic acid using cyanine dyes | FUJI PHOTO FILM CO., LTD. (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1322710-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Molecular Probes Inc. (US) | 2003-07-02 | — | — | EP | disclosed |
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-06-20 | — | — | US | disclosed |
| US-20020064794-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-05-30 | — | — | US | disclosed |
| WO-2002026891-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | MOLECULAR PROBES, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | KMT2A 2895/4885NPC1 2746/4885L3MBTL1 3018/4885 |
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | KMT2A 574/4885NPC1 3034/4885L3MBTL1 879/4885 |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | KMT2A 2895/4885NPC1 2746/4885L3MBTL1 3018/4885 |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | KMT2A 574/4885NPC1 3034/4885L3MBTL1 879/4885 |
| US-10633542-B2 | Azacyanine dyes and use thereof | INMT, AZI2, MYADM | KMT2A 574/4885NPC1 3034/4885L3MBTL1 879/4885 |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | KMT2A 574/4885NPC1 3034/4885L3MBTL1 879/4885 |
| US-20060004188-A1 | Intermediates and the synthesis of modified carbocyanine dyes and their conjugates | CBR3, IK, CYBA | KMT2A 3170/4885NPC1 2378/4885L3MBTL1 3229/4885 |
| US-20060099638-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | KMT2A 2895/4885NPC1 2746/4885L3MBTL1 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.