Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.51 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045049 | 0.94 | LPAR3 (0.54) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL19979611 | 0.87 | LPAR3 (0.47) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL19979602 | 0.85 | LPAR3 (0.45) | LPAR3LPAR2LPAR1P2RY10 | |
| Trolamine SCHEMBL4931824 | 0.82 | LPAR3 (0.72) | LPAR3LPAR2LPAR1ENPP2 | |
| Trolamine SCHEMBL4931834 | 0.82 | LPAR3 (0.72) | LPAR3LPAR2LPAR1ENPP2 | |
| SCHEMBL19979608 | 0.82 | LPAR3 (0.46) | LPAR3LPAR2LPAR1 | |
| SCHEMBL19979597 | 0.80 | CYP3A4 (0.45) | LPAR3LPAR2LPAR1 | |
| SCHEMBL29791453 | 0.80 | LPAR3 (0.68) | LPAR3LPAR2LPAR1ENPP2 | |
| SCHEMBL20049675 | 0.79 | LPAR3 (0.42) | LPAR3LPAR2LPAR1 | |
| Trolamine SCHEMBL21633803 | 0.78 | LPAR3 (0.53) | LPAR3LPAR2LPAR1P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053407-A1 | NOVEL AMINOBISPHOSPHONATE ANTIWEAR ADDITIVES | AFTON CHEMICAL CORPORATION (US) | 2018-03-22 | — | — | WO | disclosed |