Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.54 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979596 | 0.94 | LPAR3 (0.51) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL19979611 | 0.93 | LPAR3 (0.47) | LPAR3LPAR2LPAR1P2RY10CNR2 | |
| SCHEMBL19979602 | 0.91 | LPAR3 (0.45) | LPAR3LPAR2LPAR1P2RY10CNR2 | |
| SCHEMBL19979597 | 0.85 | CYP3A4 (0.45) | LPAR3LPAR2LPAR1 | |
| Trolamine SCHEMBL4931824 | 0.84 | LPAR3 (0.72) | LPAR3LPAR2LPAR1 | |
| Trolamine SCHEMBL4931834 | 0.84 | LPAR3 (0.72) | LPAR3LPAR2LPAR1 | |
| SCHEMBL20049675 | 0.84 | LPAR3 (0.42) | LPAR3LPAR2LPAR1 | |
| SCHEMBL29791453 | 0.82 | LPAR3 (0.68) | LPAR3LPAR2LPAR1 | |
| SCHEMBL14775348 | 0.82 | CYP3A4 (0.45) | LPAR3LPAR2LPAR1 | |
| SCHEMBL26345302 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1P2RY10TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414784-B2 | Aminobisphosphonate antiwear additives | AFTON CHEMICAL CORPORATION (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180099985-A1 | Novel AminoBisPhosphonate Antiwear Additives | AFTON CHEMICAL CORP (US) | 2018-04-12 | — | — | US | disclosed |
| US-20180099985-A1 | Novel AminoBisPhosphonate Antiwear Additives | AFTON CHEMICAL CORP (US) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099985-A1 | Novel AminoBisPhosphonate Antiwear Additives | SOST, PSPH, FIBP | LPAR3 1425/4885LPAR2 2993/4885LPAR1 1732/4885 |
| US-10414784-B2 | Aminobisphosphonate antiwear additives | SOST, AASDHPPT, SLC35B2 | LPAR3 1673/4885LPAR2 3267/4885LPAR1 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.