Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.45 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045049 | 0.91 | LPAR3 (0.54) | LPAR3LPAR2LPAR1P2RY10FAAH | |
| SCHEMBL19979596 | 0.85 | LPAR3 (0.51) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL19979611 | 0.84 | LPAR3 (0.47) | LPAR3LPAR2LPAR1P2RY10FAAH | |
| SCHEMBL19979597 | 0.77 | CYP3A4 (0.45) | LPAR3LPAR2LPAR1 | |
| Trolamine SCHEMBL4931824 | 0.76 | LPAR3 (0.72) | LPAR3LPAR2LPAR1 | |
| Trolamine SCHEMBL4931834 | 0.76 | LPAR3 (0.72) | LPAR3LPAR2LPAR1 | |
| SCHEMBL20049675 | 0.76 | LPAR3 (0.42) | LPAR3LPAR2LPAR1 | |
| SCHEMBL29791453 | 0.74 | LPAR3 (0.68) | LPAR3LPAR2LPAR1 | |
| SCHEMBL14775348 | 0.74 | CYP3A4 (0.45) | LPAR3LPAR2LPAR1 | |
| SCHEMBL14760582 | 0.73 | LPAR3 (0.51) | LPAR3LPAR2LPAR1P2RY10FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053407-A1 | NOVEL AMINOBISPHOSPHONATE ANTIWEAR ADDITIVES | AFTON CHEMICAL CORPORATION (US) | 2018-03-22 | — | — | WO | disclosed |