Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002017 | 0.83 | HSD17B1 (0.41) | HSD17B1ESR1ESR2NPC1RAB9A | |
| SCHEMBL14838335 | 0.78 | ESR1 (0.44) | MAPTALDH1A1POLBHSD17B1KDM4E | |
| SCHEMBL916777 | 0.76 | HSD17B1 (0.47) | MAPTALDH1A1HSD17B1KDM4EESR1 | |
| SCHEMBL14838368 | 0.72 | ESR1 (0.36) | MAPTALDH1A1POLBHSD17B1TP53 | |
| SCHEMBL16021787 | 0.72 | HSD17B1 (0.40) | MAPTHSD17B1ESR1ESR2PTP4A3 | |
| SCHEMBL14838323 | 0.72 | HSD17B1 (0.41) | MAPTALDH1A1HSD17B1ESR1ESR2 | |
| SCHEMBL14838518 | 0.71 | HSD17B1 (0.42) | ALDH1A1POLBHSD17B1ESR1ESR2 | |
| SCHEMBL14838269 | 0.71 | HSD17B1 (0.42) | MAPTHSD17B1KDM4ENPSR1ESR1 | |
| SCHEMBL14838329 | 0.71 | HSD17B1 (0.39) | MAPTALDH1A1HSD17B1ESR1ESR2 | |
| SCHEMBL21291302 | 0.71 | HSD17B1 (0.32) | HSD17B1PTP4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440967-B1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MAT INC (CA) | 2018-03-21 | — | — | EP | disclosed |