Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.39 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838335 | 0.94 | ESR1 (0.44) | HSD17B1PTP4A3ESR1ESR2PTP4A2 | |
| SCHEMBL916777 | 0.91 | HSD17B1 (0.47) | HSD17B1PTP4A3ESR1ESR2PTP4A2 | |
| SCHEMBL14838323 | 0.86 | HSD17B1 (0.41) | HSD17B1PTP4A3ESR1ESR2PTP4A2 | |
| SCHEMBL21291302 | 0.85 | HSD17B1 (0.32) | HSD17B1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL14838368 | 0.84 | ESR1 (0.36) | HSD17B1ESR1ESR2CYP1A2HSD17B2 | |
| SCHEMBL16021787 | 0.84 | HSD17B1 (0.40) | HSD17B1PTP4A3ESR1ESR2PTP4A2 | |
| SCHEMBL19979600 | 0.83 | MAPT (0.34) | HSD17B1PTP4A3ESR1ESR2NPC1 | |
| SCHEMBL14838322 | 0.83 | HSD17B1 (0.43) | HSD17B1PTP4A3ESR1ESR2PTP4A2 | |
| SCHEMBL14838329 | 0.83 | HSD17B1 (0.39) | HSD17B1PTP4A3ESR1ESR2PTP4A2 | |
| SCHEMBL14838518 | 0.83 | HSD17B1 (0.42) | HSD17B1PTP4A3ESR1ESR2PTP4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690045-B | Diarylethene compounds and uses thereof | 首诺加拿大公司 | 2022-08-30 | — | — | CN | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| US-20200033687-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MAT INC (CA) | 2020-01-30 | — | — | US | disclosed |
| US-10416521-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2019-09-17 | — | — | US | disclosed |
| EP-3385354-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | Switch Materials, Inc. (CA) | 2018-10-10 | — | — | EP | disclosed |
| US-20180210308-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SOLUTIA CANADA INC. (CA) | 2018-07-26 | — | — | US | disclosed |
| US-20180210308-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SOLUTIA CANADA INC. (CA) | 2018-07-26 | — | — | US | disclosed |
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |
| US-9864252-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2018-01-09 | — | — | US | disclosed |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-20130208333-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2013-08-15 | — | — | US | disclosed |
| US-8441707-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2013-05-14 | — | — | US | disclosed |
| US-8441707-B2 | Variable transmittance optical filter and uses thereof | SWITCH MATERIALS, INC. (CA) | 2013-05-14 | — | — | US | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| US-20120044560-A9 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20120044560-A9 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20100315693-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2010-12-16 | — | — | US | disclosed |
| US-20100315693-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | HSD17B1 1685/4885PTP4A3 2139/4885ESR1 1818/4885 |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | HSD17B1 1685/4885PTP4A3 2139/4885ESR1 1818/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | HSD17B1 1685/4885PTP4A3 2139/4885ESR1 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.