Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768655 | 0.72 | NAAA (0.65) | NAAAALDH1A1HTTEPHX1 | |
| SCHEMBL13972986 | 0.71 | CA12 (0.31) | EPHX1 | |
| SCHEMBL4455041 | 0.70 | NAAA (0.38) | NAAAALDH1A1HTT | |
| SCHEMBL29117609 | 0.70 | NAAA (0.57) | NAAAALDH1A1HTTEPHX1 | |
| SCHEMBL9009690 | 0.70 | NAAA (0.57) | NAAAALDH1A1HTTEPHX1 | |
| SCHEMBL29117608 | 0.68 | NAAA (0.50) | NAAAALDH1A1HTTEPHX1 | |
| SCHEMBL4743688 | 0.68 | NAAA (0.58) | NAAAALDH1A1HTTEPHX1 | |
| SCHEMBL27593606 | 0.68 | EPHX1 (0.41) | NAAAHTTEPHX1 | |
| SCHEMBL4978860 | 0.67 | NAAA (0.86) | NAAAALDH1A1HTTEPHX1 | |
| SCHEMBL28473788 | 0.67 | NAAA (0.63) | NAAAALDH1A1HTTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342771-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-11-25 | — | — | EP | disclosed |
| EP-3375780-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |
| EP-2956452-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-03-21 | — | — | EP | disclosed |