SCHEMBL4455041

SCHEMBL4455041

C=C(C=C(CCCC)C(=O)O)C(=O)OC1CC1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.38
APEX1 P27695 3/20 0.35
ALOX5 P09917 4/20 0.33
PTGES O14684 3/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
PPARG P37231 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8997946 0.78 APEX1 (0.40) APEX1ALDH1A1PPARGMEN1KMT2A
SCHEMBL6131250 0.75 TSHR (0.41) APEX1ALOX5PTGESALDH1A1PPARG
SCHEMBL7943868 0.75 TSHR (0.53) NAAAAPEX1
SCHEMBL294193 0.73
SCHEMBL5071327 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8348270 0.72 GPR84 (0.47) APEX1ALDH1A1PPARGMEN1POLB
SCHEMBL6710667 0.71 TSHR (0.41) APEX1ALOX5PTGESALDH1A1PPARG
SCHEMBL8008242 0.71 ALDH1A1 (0.47) ALDH1A1
SCHEMBL19980164 0.70 NAAA (0.43) NAAAALDH1A1HTT
SCHEMBL5166725 0.70 ALDH1A1 (0.34) APEX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556857-B2 Polymeric additives for enhancement of ballistic performance in fibrous structures E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-07 US disclosed
US-20050282450-A1 Polymeric additives for enhancement of ballistic performance in fibrous structures DUPONT SAFETY & CONSTRUCTION, INC. 2005-12-22 US disclosed