Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26006720 | 0.87 | DRD2 (0.36) | PTGDR2DRD2SLC6A4HTR1BHTR1A | |
| SCHEMBL25135242 | 0.85 | KCNH2 (0.42) | DRD2SLC6A4HTR1BHTR1ASLC6A2 | |
| SCHEMBL26005471 | 0.83 | DRD2 (0.37) | DRD2SLC6A4HTR1BHTR1AHTR6 | |
| SCHEMBL19972494 | 0.82 | PTGDR2 (0.36) | PTGDR2DRD2SLC6A4HTR1BHTR1A | |
| SCHEMBL19972663 | 0.82 | PTGDR2 (0.36) | PTGDR2DRD2SLC6A4HTR1BHTR1A | |
| SCHEMBL19972650 | 0.82 | PTGDR2 (0.36) | PTGDR2DRD2SLC6A4HTR1BHTR1A | |
| SCHEMBL25135361 | 0.82 | KDM4E (0.33) | DRD2KDM4EALDH1A1 | |
| SCHEMBL19980726 | 0.80 | HTR6 (0.39) | DRD2HTR2AHTR6 | |
| SCHEMBL31001668 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1 | |
| SCHEMBL19972493 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230627-A2 | INHIBITORS OF THE MENIN-MLL INTERACTION | Vitae Pharmaceuticals, LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2018053267-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |