Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980649 | 0.78 | MAPT (0.33) | MAPTMAPK1NPSR1 | |
| SCHEMBL25135200 | 0.75 | KDM4E (0.44) | MAPT | |
| SCHEMBL20684923 | 0.69 | KDM5A (0.37) | MAPTMAPK1NPSR1 | |
| SCHEMBL11281524 | 0.67 | HTT (0.47) | MAPT | |
| SCHEMBL18983725 | 0.66 | ESR1 (0.46) | RORC | |
| SCHEMBL19941849 | 0.64 | CYP2A6 (0.38) | MAPTMAPK1RORC | |
| SCHEMBL24317094 | 0.64 | ATM (0.42) | — | |
| SCHEMBL14401880 | 0.63 | ALDH1A1 (0.48) | MAPTMAPK1 | |
| SCHEMBL936470 | 0.62 | CYP19A1 (0.49) | RORC | |
| SCHEMBL11593770 | 0.62 | MAPT (0.41) | MAPTMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053267-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |