Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980704 | 0.78 | MAPT (0.34) | MAPTMAPK1NPSR1 | |
| SCHEMBL309292 | 0.78 | KIF11 (0.45) | ALDH1A1TSHREGFRKDM4EPTGS2 | |
| SCHEMBL25135200 | 0.76 | KDM4E (0.44) | MAPTALDH1A1KDM4ERAB9AKIF11 | |
| SCHEMBL22298702 | 0.69 | ALDH1A1 (0.37) | MAPTALDH1A1TSHRKDM4EPTGS2 | |
| SCHEMBL472590 | 0.69 | EGFR (0.44) | NPSR1ALDH1A1EGFRKDM4ECYP2A6 | |
| SCHEMBL31270677 | 0.67 | KDM5A (0.58) | MAPTMAPK1ALDH1A1TSHREGFR | |
| SCHEMBL2517047 | 0.67 | ALDH1A1 (0.41) | ALDH1A1RAB9ACYP2A6 | |
| SCHEMBL8067987 | 0.65 | CYP19A1 (0.38) | EGFR | |
| SCHEMBL11328597 | 0.64 | ALDH1A1 (0.42) | NPSR1ALDH1A1TSHRKDM4EPTGS2 | |
| SCHEMBL393655 | 0.64 | MAPT (0.40) | MAPTMAPK1NPSR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512850-B1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS LLC (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2018053267-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |