Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 3/20 | 0.56 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | CCL2 | P13500 | 1/20 | 0.50 |
| ▸ | CCL5 | P13501 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218171 | 0.89 | IGF2R (0.59) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL19980831 | 0.89 | IGF2R (0.54) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL19980817 | 0.89 | IGF2R (0.54) | IGF2RALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL19980886 | 0.88 | IGF2R (0.53) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL19980877 | 0.88 | IGF2R (0.53) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL18122114 | 0.86 | IGF2R (0.53) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL9218137 | 0.83 | IGF2R (0.67) | IGF2RALDH1A1CD209AMY1ALGALS3 | |
| SCHEMBL16126954 | 0.83 | IGF2R (0.67) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL19980873 | 0.82 | IGF2R (0.46) | IGF2RALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL21083292 | 0.82 | IGF2R (0.65) | IGF2RCXCL10CXCL8CCL2CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10688169-B2 | Vaccines against carbapenem-resistant Klebsiella pneumoniae | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-06-23 | — | — | US | disclosed |
| US-20180078630-A1 | VACCINES AGAINST CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10688169-B2 | Vaccines against carbapenem-resistant Klebsiella pneumoniae | UBXN1, FUT5, SLC11A2 | IGF2R 576/4885CXCL10 500/4885CXCL8 2093/4885 |
| US-20180078630-A1 | VACCINES AGAINST CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE | UBXN1, FUT5, SLC11A2 | IGF2R 576/4885CXCL10 500/4885CXCL8 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.