Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 2/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.41 |
| ▸ | SELE | P16581 | 3/20 | 0.40 |
| ▸ | SELL | P14151 | 2/20 | 0.37 |
| ▸ | SELP | P16109 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122118 | 0.87 | IGF2R (0.43) | IGF2RCD209ALDH1A1HSD17B10 | |
| SCHEMBL19980831 | 0.84 | IGF2R (0.54) | IGF2RAMY1ACD209SELESELL | |
| SCHEMBL24107790 | 0.83 | IGF2R (0.52) | IGF2RCD209ALDH1A1ALOX15 | |
| SCHEMBL19980886 | 0.83 | IGF2R (0.53) | IGF2RAMY1ACD209SELESELL | |
| SCHEMBL19980877 | 0.83 | IGF2R (0.53) | IGF2RAMY1ACD209SELESELL | |
| SCHEMBL19980809 | 0.82 | IGF2R (0.56) | IGF2RAMY1ACD209SELESELL | |
| SCHEMBL19980817 | 0.82 | IGF2R (0.54) | IGF2RAMY1ACD209SELESELL | |
| SCHEMBL24107897 | 0.80 | CD209 (0.53) | IGF2RCD209ALDH1A1 | |
| SCHEMBL19980833 | 0.80 | SELE (0.48) | IGF2RAMY1ASELESELLSELP | |
| SCHEMBL24250552 | 0.78 | SELE (0.45) | IGF2RAMY1ACD209SELESELL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10688169-B2 | Vaccines against carbapenem-resistant Klebsiella pneumoniae | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-06-23 | — | — | US | disclosed |
| US-20180078630-A1 | VACCINES AGAINST CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10688169-B2 | Vaccines against carbapenem-resistant Klebsiella pneumoniae | UBXN1, FUT5, SLC11A2 | IGF2R 576/4885AMY1A 3497/4885CD209 344/4885 |
| US-20180078630-A1 | VACCINES AGAINST CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE | UBXN1, FUT5, SLC11A2 | IGF2R 576/4885AMY1A 3497/4885CD209 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.