Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | AMY2A | P04746 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18323930 | 0.96 | AMY1A (0.48) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL17773086 | 0.96 | AMY1A (0.48) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL17773088 | 0.96 | AMY1A (0.48) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL17773089 | 0.96 | AMY1A (0.48) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL17773084 | 0.96 | AMY1A (0.48) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL16904113 | 0.96 | AMY1A (0.48) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL16904112 | 0.89 | AMY1A (0.38) | AMY1AALDH1A1MAPTALOX15 | |
| SCHEMBL19335015 | 0.88 | AMY1A (0.50) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL19980843 | 0.87 | AMY1A (0.36) | AMY1AALDH1A1MAPTALOX15STAT3 | |
| SCHEMBL22130487 | 0.87 | AMY1A (0.36) | AMY1AALDH1A1MAPTALOX15STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10688169-B2 | Vaccines against carbapenem-resistant Klebsiella pneumoniae | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-06-23 | — | — | US | disclosed |
| US-20180078630-A1 | VACCINES AGAINST CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10688169-B2 | Vaccines against carbapenem-resistant Klebsiella pneumoniae | UBXN1, FUT5, SLC11A2 | AMY1A 3497/4885ALDH1A1 2614/4885MAPT 2070/4885 |
| US-20180078630-A1 | VACCINES AGAINST CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE | UBXN1, FUT5, SLC11A2 | AMY1A 3497/4885ALDH1A1 2614/4885MAPT 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.