Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980921 | 0.90 | PHLPP2 (0.44) | PHLPP2TDP1POLBAPEX1HTT | |
| SCHEMBL19980947 | 0.85 | ALDH1A1 (0.44) | TDP1TSHRCYP3A4ALDH1A1PSMD14 | |
| SCHEMBL19980954 | 0.85 | PHLPP2 (0.40) | PHLPP2TDP1POLBAPEX1HTT | |
| SCHEMBL19981017 | 0.85 | PHLPP2 (0.40) | PHLPP2TDP1POLBAPEX1HTT | |
| SCHEMBL19903970 | 0.83 | TSHR (0.49) | PHLPP2TDP1POLBAPEX1HTT | |
| SCHEMBL19980948 | 0.82 | PHLPP2 (0.39) | PHLPP2TDP1POLBAPEX1HTT | |
| SCHEMBL18633382 | 0.81 | PHLPP2 (0.38) | PHLPP2TDP1POLBAPEX1HTT | |
| SCHEMBL3192372 | 0.77 | CA1 (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL31582668 | 0.76 | POLB (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11980056 | 0.75 | PHLPP2 (0.49) | PHLPP2TDP1TSHRMAOACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |