Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980921 | 0.92 | PHLPP2 (0.44) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL19980954 | 0.87 | PHLPP2 (0.40) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL19981017 | 0.87 | PHLPP2 (0.40) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL19903970 | 0.85 | TSHR (0.49) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL18633382 | 0.84 | PHLPP2 (0.38) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL19980943 | 0.82 | PHLPP2 (0.37) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL3192372 | 0.79 | CA1 (0.43) | TSHRNPSR1TDP1POLBAPEX1 | |
| SCHEMBL31582668 | 0.78 | POLB (0.44) | TSHRCYP2D6TDP1POLBAPEX1 | |
| SCHEMBL11980056 | 0.77 | PHLPP2 (0.49) | PHLPP2TSHRCYP2D6MAOAHTR3A | |
| SCHEMBL19904003 | 0.77 | PHLPP2 (0.33) | PHLPP2TSHRCYP2D6MAOAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |