Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903969 | 0.85 | TSHR (0.35) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL19980921 | 0.84 | PHLPP2 (0.44) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL19981017 | 0.79 | PHLPP2 (0.40) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL19980954 | 0.79 | PHLPP2 (0.40) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL19903970 | 0.78 | TSHR (0.49) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL19980948 | 0.77 | PHLPP2 (0.39) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL18633382 | 0.76 | PHLPP2 (0.38) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL19980943 | 0.75 | PHLPP2 (0.37) | PHLPP2CYP2D6TSHRMAOAHTR3A | |
| SCHEMBL3192372 | 0.72 | CA1 (0.43) | TSHRNPSR1POLBAPEX1HTT | |
| SCHEMBL1011794 | 0.71 | POLB (0.41) | CYP2D6TSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233944-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-09-04 | — | — | EP | disclosed |
| EP-2393849-B1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-06-19 | — | — | EP | disclosed |
| EP-2393851-B1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |