SCHEMBL19981048

SCHEMBL19981048

CC(C)(S)CC(C)(C)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
MAPK1 P28482 1/20 0.41
SHBG P04278 1/20 0.40
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
KCNN4 O15554 4/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20754322 0.87 SHBG (0.50) TAAR1SHBGHIF1AESR1ESR2
SCHEMBL42933 0.80 SHBG (0.60) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL2270630 0.78 TAAR1 (0.56) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL29291029 0.76 TAAR1 (0.54) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL21245467 0.76 TAAR1 (0.54) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL8529366 0.76 TAAR1 (0.54) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL7765635 0.76 TAAR1 (0.54) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL9250206 0.76 TAAR1 (0.54) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL19033678 0.76 TAAR1 (0.60) TAAR1MAPK1SHBGCYP2C19HIF1A
SCHEMBL8730213 0.75 TAAR1 (0.58) TAAR1MAPK1CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079719-A1 NOVEL THIOL COMPOUND COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079719-A1 NOVEL THIOL COMPOUND COMPOSITION FOR OPTICAL MATERIAL TMT1A, TXNL1, C5 TAAR1 1518/4885MAPK1 3320/4885SHBG 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.