Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560711 | 0.84 | MEN1 (0.37) | ALDH1A1MAPTSMN1; SMN2KDM4EPKM | |
| SCHEMBL21921032 | 0.77 | — | — | |
| SCHEMBL13543497 | 0.74 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19865533 | 0.72 | MEN1 (0.39) | ALDH1A1MAPTSMN1; SMN2KDM4EPKM | |
| SCHEMBL19560661 | 0.70 | MEN1 (0.37) | ALDH1A1MAPTSMN1; SMN2KDM4EPKM | |
| SCHEMBL15265943 | 0.69 | AKR1B1 (0.45) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL15265940 | 0.69 | AKR1B1 (0.45) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL389017 | 0.69 | — | — | |
| SCHEMBL19560656 | 0.68 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL22057084 | 0.68 | MMP1 (0.32) | CTSDALDH1A1SMN1; SMN2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052936-A1 | THERAPEUTIC ACRYLATES AS ENHANCED MEDICAL ADHESIVES | CARNEGIE MELLON UNIVERSITY (US) | 2018-03-22 | — | — | WO | disclosed |