Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981145 | 0.79 | BMP1 (0.49) | BMP1DPP4DPP7CTPS1TDP1 | |
| SCHEMBL18078143 | 0.75 | VSIR (0.52) | BMP1 | |
| SCHEMBL22677564 | 0.74 | VSIR (0.43) | BMP1 | |
| SCHEMBL19867031 | 0.72 | VSIR (0.63) | LMNATSHRDPP4DPP7TDP1 | |
| SCHEMBL19450457 | 0.72 | VSIR (0.63) | LMNATSHRDPP4DPP7TDP1 | |
| SCHEMBL18077945 | 0.72 | VSIR (0.63) | LMNATSHRDPP4DPP7TDP1 | |
| SCHEMBL19981138 | 0.71 | BMP1 (0.49) | BMP1DPP4DPP7CTPS1TDP1 | |
| SCHEMBL18078168 | 0.71 | VSIR (0.49) | BMP1 | |
| SCHEMBL5420455 | 0.67 | NPC1 (0.45) | LMNATSHRHCAR2DPP4DPP7 | |
| SCHEMBL19984807 | 0.67 | TP53 (0.43) | LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |