Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981250 | 0.89 | VSIR (0.44) | VSIRCD274P2RY12PDCD1LG2SRC | |
| SCHEMBL19981232 | 0.89 | VSIR (0.44) | VSIRCD274ACACBPDCD1LG2SRC | |
| SCHEMBL19866994 | 0.86 | VSIR (0.47) | VSIRCD274PDCD1LG2SRC | |
| SCHEMBL18077930 | 0.86 | VSIR (0.47) | VSIRCD274PDCD1LG2SRC | |
| SCHEMBL28776794 | 0.78 | CD274 (0.47) | VSIRCD274PDCD1LG2SRCPDCD1 | |
| SCHEMBL28776802 | 0.78 | CD274 (0.47) | VSIRCD274PDCD1LG2SRCPDCD1 | |
| SCHEMBL28776810 | 0.78 | CD274 (0.47) | VSIRCD274PDCD1LG2SRCPDCD1 | |
| SCHEMBL19866992 | 0.77 | CD274 (0.53) | VSIRCD274PDCD1LG2PDCD1 | |
| SCHEMBL18077951 | 0.77 | CD274 (0.53) | VSIRCD274PDCD1LG2PDCD1 | |
| SCHEMBL19867089 | 0.75 | CD274 (0.57) | VSIRCD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |