Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.47 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.47 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776810 | 1.00 | CD274 (0.47) | CD274VSIRPDCD1LG2PDCD1SRC | |
| SCHEMBL28776794 | 1.00 | CD274 (0.47) | CD274VSIRPDCD1LG2PDCD1SRC | |
| SCHEMBL28776875 | 0.88 | CD274 (0.62) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL28776872 | 0.88 | CD274 (0.62) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL28776811 | 0.83 | CD274 (0.38) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL28776816 | 0.83 | CD274 (0.38) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL28776825 | 0.83 | CD274 (0.38) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL19981155 | 0.78 | VSIR (0.44) | CD274VSIRPDCD1LG2PDCD1SRC | |
| SCHEMBL18735738 | 0.77 | CD274 (0.76) | CD274VSIRPDCD1LG2PDCD1SRC | |
| SCHEMBL16557042 | 0.77 | CD274 (0.76) | CD274VSIRPDCD1LG2PDCD1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794422-B | Heterocyclic compounds as PD-L1 inhibitors | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |