Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981254 | 0.88 | KCNT1 (0.47) | VSIRCD274LMNATSHRIDH1 | |
| SCHEMBL18077932 | 0.86 | VSIR (0.43) | VSIRCD274LMNATSHRHDAC6 | |
| SCHEMBL19867036 | 0.86 | VSIR (0.43) | VSIRCD274LMNATSHRHDAC6 | |
| SCHEMBL19981275 | 0.85 | DPP4 (0.47) | VSIRCD274LMNATSHRIDH1 | |
| SCHEMBL19866982 | 0.78 | VSIR (0.45) | VSIRCD274LMNATSHR | |
| SCHEMBL18077937 | 0.78 | VSIR (0.45) | VSIRCD274LMNATSHR | |
| SCHEMBL19867021 | 0.77 | VSIR (0.48) | VSIRCD274S1PR1 | |
| SCHEMBL18077943 | 0.77 | VSIR (0.48) | VSIRCD274S1PR1 | |
| SCHEMBL18077933 | 0.76 | CD274 (0.58) | VSIRCD274LMNATSHRIDH1 | |
| SCHEMBL19867027 | 0.76 | CD274 (0.58) | VSIRCD274LMNATSHRIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |