Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.42 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981254 | 0.90 | KCNT1 (0.47) | FFAR1IDH1VSIRCD274LMNA | |
| SCHEMBL19981256 | 0.85 | VSIR (0.44) | FFAR1IDH1VSIRCD274LMNA | |
| SCHEMBL19867036 | 0.79 | VSIR (0.43) | DPP4DPP7VSIRCD274LMNA | |
| SCHEMBL18077932 | 0.79 | VSIR (0.43) | DPP4DPP7VSIRCD274LMNA | |
| SCHEMBL18077933 | 0.77 | CD274 (0.58) | IDH1VSIRCD274LMNATSHR | |
| SCHEMBL19867027 | 0.77 | CD274 (0.58) | IDH1VSIRCD274LMNATSHR | |
| SCHEMBL19866982 | 0.76 | VSIR (0.45) | VSIRCD274LMNATSHRKCNT1 | |
| SCHEMBL18077937 | 0.76 | VSIR (0.45) | VSIRCD274LMNATSHRKCNT1 | |
| SCHEMBL19962773 | 0.74 | CD274 (0.60) | VSIRCD274 | |
| SCHEMBL19969881 | 0.74 | CD274 (0.60) | VSIRCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |