Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18077936 | 0.86 | CD274 (0.58) | VSIRCD274DPP4DPP7S1PR1 | |
| SCHEMBL19867093 | 0.86 | CD274 (0.58) | VSIRCD274DPP4DPP7S1PR1 | |
| SCHEMBL19981133 | 0.86 | DPP4 (0.36) | VSIRCD274DPP4DPP7S1PR1 | |
| SCHEMBL19981159 | 0.79 | DPP4 (0.38) | DPP4DPP7S1PR1SLC9A1IDH1 | |
| SCHEMBL24476314 | 0.79 | DPP4 (0.39) | DPP4DPP7S1PR1SLC9A1HDAC6 | |
| SCHEMBL19867021 | 0.79 | VSIR (0.48) | VSIRCD274DPP4DPP7S1PR1 | |
| SCHEMBL18077943 | 0.79 | VSIR (0.48) | VSIRCD274DPP4DPP7S1PR1 | |
| SCHEMBL19981329 | 0.78 | VSIR (0.44) | VSIRCD274DPP4DPP7MMP12 | |
| SCHEMBL19981143 | 0.77 | DPP4 (0.34) | DPP4DPP7S1PR1SLC9A1HDAC6 | |
| SCHEMBL18077932 | 0.76 | VSIR (0.43) | VSIRCD274DPP4DPP7S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |