Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | RRM1 | P23921 | 2/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981159 | 0.80 | DPP4 (0.38) | DPP4DPP7S1PR1SLC9A1HDAC6 | |
| SCHEMBL19981133 | 0.78 | DPP4 (0.36) | DPP4DPP7S1PR1SLC9A1HDAC6 | |
| SCHEMBL19981291 | 0.77 | VSIR (0.42) | DPP4DPP7S1PR1SLC9A1HDAC6 | |
| SCHEMBL18078016 | 0.74 | DPP4 (0.45) | DPP4DPP7S1PR1SLC9A1CTSA | |
| SCHEMBL19975480 | 0.73 | DPP4 (0.40) | DPP4DPP7S1PR1CTSA | |
| SCHEMBL19975478 | 0.73 | DPP4 (0.40) | DPP4DPP7S1PR1CTSA | |
| SCHEMBL19981240 | 0.72 | LMNA (0.40) | S1PR1HDAC6CTSA | |
| SCHEMBL24218473 | 0.71 | S1PR1 (0.35) | DPP4DPP7S1PR1CTSA | |
| SCHEMBL19867093 | 0.71 | CD274 (0.58) | DPP4DPP7S1PR1CTSA | |
| SCHEMBL18077936 | 0.71 | CD274 (0.58) | DPP4DPP7S1PR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |