Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19867021 | 0.72 | VSIR (0.48) | S1PR1GABRA5 | |
| SCHEMBL18077943 | 0.72 | VSIR (0.48) | S1PR1GABRA5 | |
| SCHEMBL1703767 | 0.72 | AKR1B1 (0.50) | CNR2CNR1S1PR1GAAHTT | |
| SCHEMBL19981160 | 0.71 | S1PR1 (0.42) | CNR2CNR1S1PR1MAPTLMNA | |
| SCHEMBL18077932 | 0.70 | VSIR (0.43) | CNR2CNR1S1PR1LMNAGABRA5 | |
| SCHEMBL19867036 | 0.70 | VSIR (0.43) | CNR2CNR1S1PR1LMNAGABRA5 | |
| SCHEMBL18077936 | 0.70 | CD274 (0.58) | S1PR1GABRA5 | |
| SCHEMBL19867093 | 0.70 | CD274 (0.58) | S1PR1GABRA5 | |
| SCHEMBL19981314 | 0.70 | ACLY (0.41) | CNR2CNR1S1PR1MAPTLMNA | |
| SCHEMBL773983 | 0.70 | AKR1B1 (0.47) | S1PR1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |