Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981348 | 1.00 | VSIR (0.40) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL20057097 | 0.89 | CD274 (0.43) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL20057121 | 0.89 | CD274 (0.43) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058548 | 0.81 | CD274 (0.52) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL20057117 | 0.80 | CD274 (0.48) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL20057111 | 0.80 | CD274 (0.48) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL19969046 | 0.79 | CD274 (0.53) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL24086161 | 0.79 | CD274 (0.53) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058469 | 0.79 | CD274 (0.47) | VSIRCD274MAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058471 | 0.79 | CD274 (0.47) | VSIRCD274MAPK1TSHRPDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |