Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.43 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057121 | 1.00 | CD274 (0.43) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL19981346 | 0.89 | VSIR (0.40) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL19981348 | 0.89 | VSIR (0.40) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058882 | 0.86 | ACACB (0.33) | SMN1; SMN2MAPT | |
| SCHEMBL24058548 | 0.84 | CD274 (0.52) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL20057111 | 0.83 | CD274 (0.48) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL20057117 | 0.83 | CD274 (0.48) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058471 | 0.82 | CD274 (0.47) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058469 | 0.82 | CD274 (0.47) | CD274VSIRMAPK1TSHRPDCD1LG2 | |
| SCHEMBL24058461 | 0.81 | MAPT (0.49) | MAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363790-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2020-02-19 | — | — | EP | disclosed |
| EP-3041827-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-04-18 | — | — | EP | disclosed |