Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19442030 | 0.84 | ALDH1A1 (0.50) | PHLPP2ALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL18914738 | 0.83 | HTT (0.58) | HTTALDH1A1GAAHPGDTSHR | |
| SCHEMBL19981293 | 0.83 | ALDH1A1 (0.49) | HTTPHLPP2ALDH1A1GAAMAPK1 | |
| SCHEMBL18104617 | 0.81 | HTT (0.56) | HTTALDH1A1GAAMAPK1HPGD | |
| SCHEMBL21401922 | 0.81 | HTT (0.59) | HTTALDH1A1HPGDTSHRMAPT | |
| SCHEMBL17693443 | 0.80 | HTT (0.54) | HTTALDH1A1GAAHPGDTSHR | |
| SCHEMBL28426282 | 0.79 | TSHR (0.53) | HTTALDH1A1MAPK1HSD17B10HPGD | |
| SCHEMBL69791 | 0.78 | HTT (0.69) | HTTALDH1A1GAAHPGDTSHR | |
| SCHEMBL8963375 | 0.78 | PHLPP2 (0.73) | PHLPP2ALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL28427399 | 0.78 | HDAC4 (0.65) | HTTALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053372-A1 | POLYMERS AND METHODS OF PRODUCING THEREOF | MICROMIDAS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |