Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981453 | 0.84 | HTT (0.51) | ALDH1A1GAAPHLPP2HSD17B10MAPK1 | |
| SCHEMBL28817945 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL19442031 | 0.81 | HTT (0.40) | ALDH1A1HSD17B10MAPTSMN1; SMN2KDM4E | |
| SCHEMBL991408 | 0.81 | MEN1 (0.63) | ALDH1A1PHLPP2HSD17B10MAPK1MAPT | |
| SCHEMBL11985077 | 0.80 | TSHR (0.50) | ALDH1A1HSD17B10MAPK1SMN1; SMN2LMNA | |
| SCHEMBL28817917 | 0.79 | HDAC4 (0.57) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL19981293 | 0.77 | ALDH1A1 (0.49) | ALDH1A1GAAPHLPP2HSD17B10MAPK1 | |
| SCHEMBL19825337 | 0.76 | TSHR (0.45) | ALDH1A1MAPK1MAPTCYP1A2 | |
| SCHEMBL19825409 | 0.75 | TSHR (0.44) | ALDH1A1MAPK1MAPT | |
| SCHEMBL19442049 | 0.75 | HTT (0.58) | ALDH1A1GAAMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782382-B2 | TOFA analogs useful in treating dermatological disorders or conditions | DERMIRA (CANADA), INC. (US) | 2017-10-10 | — | — | US | disclosed |