Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974134 | 0.85 | RAB9A (0.66) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL19974151 | 0.85 | RAB9A (0.66) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL32690316 | 0.85 | RAB9A (0.66) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL30271553 | 0.83 | RAB9A (0.63) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19974186 | 0.82 | RAB9A (0.61) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL17844701 | 0.81 | RAB9A (0.79) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL23657159 | 0.81 | LMNA (0.74) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL23647322 | 0.80 | RAB9A (0.62) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL19974421 | 0.80 | LMNA (0.68) | RAB9ALMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL19981602 | 0.80 | RAB9A (0.62) | RAB9ALMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050656-A2 | INHIBITORS OF HEAT SHOCK FACTORS AND USES THEREOF | HSF PHARMACEUTICALS (CH) | 2018-03-22 | — | — | WO | disclosed |