Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443900 | 0.81 | ACHE (0.33) | — | |
| SCHEMBL15871549 | 0.80 | — | — | |
| SCHEMBL25775999 | 0.75 | — | — | |
| SCHEMBL19981469 | 0.75 | — | — | |
| SCHEMBL16209804 | 0.69 | KDM4E (0.33) | ALDH1A1KDM4E | |
| SCHEMBL769125 | 0.67 | KDM4E (0.36) | ALDH1A1KDM4E | |
| SCHEMBL20019698 | 0.67 | CA12 (0.33) | — | |
| SCHEMBL19981530 | 0.67 | SMN1; SMN2 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL23344666 | 0.66 | — | — | |
| SCHEMBL18933177 | 0.66 | GAA (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788487-B1 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | SAREPTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |
| EP-2788488-B1 | METHODS FOR TREATING PROGEROID LAMINOPATHIES USING OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | SAREPTA THERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |