Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 3/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19093147 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL19186343 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL19981456 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL18993199 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL19186314 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL16541580 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL19607443 | 1.00 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL19186622 | 0.94 | PRCP (0.32) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL15368147 | 0.92 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 | |
| SCHEMBL204130 | 0.92 | PRCP (0.34) | PRCPHPGDSTBK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079744-A1 | METHOD OF PREPARATION FOR LEDIPASVIR AND DERIVATIVE THEREOF, AND INTERMEDIATE COMPOUND FOR PREPARATION OF LEDIPASVIR | SHANGHAI FOREFRONT PHARMACEUTICAL CO LTD (CN) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079744-A1 | METHOD OF PREPARATION FOR LEDIPASVIR AND DERIVATIVE THEREOF, AND INTERMEDIATE COMPOUND FOR PREPARATION OF LEDIPASVIR | POLI, SAMHD1, TYMP | PRCP 750/4885HPGDS 692/4885TBK1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.