SCHEMBL19981547

SCHEMBL19981547

CCCCCN1CC(C)N(CCCCC)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CACNA1G O43497 1/20 0.39
CACNA1H O95180 1/20 0.39
CACNA1I Q9P0X4 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH2 P05091 1/20 0.38
ALDH3A1 P30838 1/20 0.38
HTR1A P08908 1/20 0.38
CES1 P23141 2/20 0.37
CDC25A P30304 1/20 0.37
BRD4 O60885 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19949917 0.76 KDM4E (0.51) KDM4ELMNAALDH1A1CYP1A2CYP2D6
Bromide SCHEMBL460851 0.75 ALDH1A1 (0.47) KDM4ELMNAALDH1A1CYP1A2CYP2D6
SCHEMBL7065366 0.74 ALDH1A1 (0.50) KDM4ELMNAALDH1A1CYP1A2CYP2D6
SCHEMBL28238080 0.74 ALDH1A1 (0.50) KDM4ELMNAALDH1A1CYP1A2CYP2D6
Bromide SCHEMBL28537895 0.73 ALDH1A1 (0.53) KDM4ELMNAALDH1A1CYP1A2CYP2D6
Bromide SCHEMBL11425322 0.73 ALDH1A1 (0.53) KDM4ELMNAALDH1A1CYP1A2CYP2D6
SCHEMBL10699214 0.72 GBA1 (0.47) ALDH1A1
SCHEMBL25387249 0.72 TDP1 (0.40) KDM4ELMNAALDH1A1CYP1A2CYP2D6
SCHEMBL21049602 0.71 ALDH1A1 (0.50) KDM4ELMNAALDH1A1CYP1A2CYP2D6
SCHEMBL28537893 0.71 CES1 (0.45) KDM4ELMNAALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018052725-A1 STABLE VIOLET-BLUE TO BLUE IMIDAZOLIUM COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2018-03-22 WO disclosed