SCHEMBL28537893

SCHEMBL28537893

CCCCCCCCCCCCCCCCN1c2ccccc2N(CCCCCCCCCCCCCCCC)C1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.45
CDC25A P30304 2/20 0.45
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH2 P05091 1/20 0.42
ALDH3A1 P30838 1/20 0.42
CNR2 P34972 3/20 0.41
CNR1 P21554 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KCNH2 Q12809 1/20 0.40
SLC9A1 P19634 2/20 0.39
PRKCG P05129 1/20 0.39
PRKCB P05771 1/20 0.39
PRKCA P17252 1/20 0.39
PRKCH P24723 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28461113 0.92 TDP1 (0.39) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL29283497 0.87 MEN1 (0.38) CES1CDC25AKDM4ELMNAALDH1A1
Bromide SCHEMBL460851 0.81 ALDH1A1 (0.47) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL459465 0.79 PRKCD (0.45) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL9722551 0.76 HTR1A (0.44) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL25387249 0.75 TDP1 (0.40) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL30141987 0.74 CDC25A (0.61) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL3635173 0.74 CDC25A (0.61) CES1CDC25AKDM4ELMNAALDH1A1
Iodide SCHEMBL5146472 0.74 PDGFRB (0.41) CES1CDC25AKDM4ELMNAALDH1A1
SCHEMBL29142651 0.74 CES1 (0.42) CES1CDC25AKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108360085-B Polyphenylene sulfide antioxidant fiber based on layered nanoparticles and preparation method thereof 安徽工程大学 2021-02-26 CN disclosed