Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303619 | 0.90 | UGT2B17 (0.40) | MAPK1GFERUGT2B17 | |
| SCHEMBL13363416 | 0.88 | UGT2B17 (0.36) | MAPK1GFERUGT2B17 | |
| SCHEMBL19981716 | 0.76 | UGT2B17 (0.38) | UGT2B17 | |
| SCHEMBL12024884 | 0.71 | UGT2B17 (0.32) | UGT2B17 | |
| SCHEMBL13303498 | 0.66 | UGT2B17 (0.47) | UGT2B17 | |
| SCHEMBL2720129 | 0.64 | MAPK1 (0.31) | MAPK1GFER | |
| SCHEMBL13351648 | 0.64 | RAB9A (0.43) | MAPK1 | |
| SCHEMBL11987733 | 0.62 | UGT2B17 (0.40) | UGT2B17 | |
| SCHEMBL11987809 | 0.62 | KCNH2 (0.41) | MAPK1UGT2B17 | |
| SCHEMBL19981490 | 0.62 | UGT2B17 (0.40) | UGT2B17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |