Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465844 | 0.76 | BTK (0.51) | BTK | |
| SCHEMBL19981742 | 0.71 | MELK (0.34) | BTK | |
| SCHEMBL19981725 | 0.68 | BTK (0.45) | BTK | |
| SCHEMBL19981932 | 0.67 | CLK1 (0.38) | BTK | |
| SCHEMBL19981750 | 0.67 | BTK (0.37) | BTK | |
| SCHEMBL19981969 | 0.67 | HDAC3 (0.38) | BTK | |
| SCHEMBL19981492 | 0.67 | BTK (0.38) | BTK | |
| SCHEMBL19981978 | 0.66 | BTK (0.32) | BTK | |
| SCHEMBL19981562 | 0.65 | SLC9A1 (0.36) | BTK | |
| SCHEMBL9984573 | 0.62 | BTK (0.74) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |