Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19847432 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL19500815 | 0.71 | ALDH1A1 (0.55) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL9057293 | 0.71 | ALDH1A1 (0.96) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL21440761 | 0.71 | TDP1 (0.53) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL23289769 | 0.70 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRMAPK1L3MBTL1 | |
| SCHEMBL24449298 | 0.70 | KMT2A (0.53) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL14002494 | 0.70 | KMT2A (0.49) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL29388715 | 0.70 | ALDH1A1 (0.89) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL50441 | 0.70 | ALDH1A1 (0.89) | ALDH1A1TDP1MMP2MMP9MMP12 | |
| SCHEMBL29171664 | 0.70 | KMT2A (0.56) | ALDH1A1TDP1MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11266674-B2 | Pharmaceutical composition for tumor treatment or prevention, method, and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-03-08 | — | — | US | disclosed |
| US-10662214-B2 | Compound of 4′-thionucleoside, as well as preparation method therefor, pharmaceutical composition thereof and application thereof | Sichuan Keiun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20200121707-A1 | PHARMACEUTICAL COMPOSITION FOR TUMOR TREATMENT OR PREVENTION, METHOD, AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-04-23 | — | — | US | disclosed |
| US-20180079770-A1 | NOVEL COMPOUND OF 4'-THIONUCLEOSIDE, AS WELL AS PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662214-B2 | Compound of 4′-thionucleoside, as well as preparation method therefor, pharmaceutical composition thereof and application thereof | TYMP, WEE1, NTPCR | ALDH1A1 3651/4885TDP1 1606/4885MMP2 4674/4885 |
| US-20180079770-A1 | NOVEL COMPOUND OF 4'-THIONUCLEOSIDE, AS WELL AS PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF | WEE1, WEE2, THEM6 | ALDH1A1 3554/4885TDP1 1554/4885MMP2 4685/4885 |
| US-20200121707-A1 | PHARMACEUTICAL COMPOSITION FOR TUMOR TREATMENT OR PREVENTION, METHOD, AND USE THEREOF | TP53, PHOSPHO1, TTR | ALDH1A1 3316/4885TDP1 1082/4885MMP2 2094/4885 |
| US-11266674-B2 | Pharmaceutical composition for tumor treatment or prevention, method, and use thereof | TP53, PHOSPHO1, TTR | ALDH1A1 3316/4885TDP1 1082/4885MMP2 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.