Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982409 | 0.90 | KDM4E (0.32) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL19982454 | 0.89 | TLR4 (0.39) | MAPTLMNAPOLBTP53PGR | |
| SCHEMBL19982456 | 0.89 | TLR4 (0.39) | MAPTLMNAPOLBTP53PGR | |
| SCHEMBL19982406 | 0.82 | TSHR (0.33) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL19982563 | 0.82 | TLR4 (0.37) | MAPTLMNAPOLBTP53PGR | |
| SCHEMBL19970531 | 0.76 | ALDH1A1 (0.33) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL19982560 | 0.75 | TLR4 (0.41) | MAPTALDH1A1GAALMNAPOLB | |
| SCHEMBL19982519 | 0.75 | TLR4 (0.41) | MAPTALDH1A1LMNAPOLBTP53 | |
| SCHEMBL19982521 | 0.75 | TLR4 (0.41) | MAPTALDH1A1LMNAPOLBTP53 | |
| SCHEMBL19982522 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296296-A1 | CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-03-21 | — | — | EP | disclosed |