Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982407 | 0.90 | MAPT (0.36) | KDM4EALDH1A1TDP1LMNAPOLB | |
| SCHEMBL19982454 | 0.83 | TLR4 (0.39) | LMNASMN1; SMN2POLBMAPTP2RX7 | |
| SCHEMBL19982456 | 0.83 | TLR4 (0.39) | LMNASMN1; SMN2POLBMAPTP2RX7 | |
| SCHEMBL19970514 | 0.78 | P2RX7 (0.32) | ALDH1A1P2RX7 | |
| SCHEMBL19982522 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL19982406 | 0.76 | TSHR (0.33) | KDM4EALDH1A1LMNAPOLBTSHR | |
| SCHEMBL19982563 | 0.76 | TLR4 (0.37) | LMNASMN1; SMN2POLBMAPTP2RX7 | |
| SCHEMBL19982457 | 0.73 | ALDH1A1 (0.32) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20111186 | 0.71 | LMNA (0.34) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL19970531 | 0.70 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296296-A1 | CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-03-21 | — | — | EP | disclosed |