Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.40 |
| ▸ | THRB | P10828 | 11/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328372 | 0.88 | THRB (0.43) | THRATHRBSMN1; SMN2 | |
| SCHEMBL13381676 | 0.83 | THRB (0.43) | THRATHRBSMN1; SMN2 | |
| SCHEMBL328509 | 0.79 | THRB (0.59) | THRATHRB | |
| SCHEMBL283411 | 0.77 | THRB (0.49) | THRATHRB | |
| SCHEMBL13381669 | 0.76 | THRB (0.53) | THRATHRB | |
| SCHEMBL328293 | 0.75 | THRB (0.52) | THRATHRB | |
| SCHEMBL283129 | 0.71 | THRB (0.76) | THRATHRB | |
| SCHEMBL13381667 | 0.70 | THRB (0.49) | THRATHRB | |
| SCHEMBL3748866 | 0.70 | THRB (0.49) | THRATHRB | |
| SCHEMBL4212904 | 0.68 | THRA (0.76) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053036-A1 | METHOD OF REDUCING THYROID-ASSOCIATED SIDE EFFECTS | VIKING THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |